To add static routes on system start-up one can use directory:
/etc/network/if-up.d/
create executable file and add required actions there, file is run right after the network interfaces are up.
e.g.
vi /etc/network/if-up.d/static-routes
#!/bin/sh
# Add static routes
#
/sbin/route add -net 192.168.1.0 netmask 255.255.255.0 gw 192.168.1.254